One Shot for Life: CRISPR Gene-Editing Shows Promise for Permanently Lowering Cholesterol

A single CRISPR gene-editing injection may one day replace a lifetime of daily statins — researchers report that 15 patients with severe high cholesterol maintained dramatically lower LDL levels for at least a year after treatment. The therapy, developed by CRISPR Therapeutics, edits a gene called ANGPTL3 that blocks the body's ability to clear bad cholesterol and triglycerides from the blood. Results published in the New England Journal of Medicine build on early data...